Of Longer Living Mice and Men
A new study sheds light on the association of branched-chain amino acids (BCAA) and longer life. Middle-aged mice given a high-BCAA diet were found to have their life spans increased by an average of 12 percent.
There is evidence that, by supplementing our own diets with BCAA, humans could achieve similar results. The oxidation and metabolic activity examined in this study is regulated by the same mechanism in both species. This could add another 10 healthy years to our lives.
A few strategies have already been shown to alleviate age-related deterioration and increase longevity. These include calorie restriction (CR) and moderate exercise. Such interventions increase the effectiveness of PGC-1α, a master regulator of mitochondrial energy metabolism, the free radical defense system and of Sirtuin 1, a protein made by the SIRT1 gene linked to life span extension, enhanced mitochondrial energy production, reaction to stress and greater free radical protection.
The study, published in the journal of Cell Metabolism, found high-BCAA diets combined with exercise produced similar effects in slowing the aging process as CR, but with the added benefits of enhanced metabolism and greatly improved antioxidant activity.
Over the years, I also have been by supplementing protein and BCAA in patients’ diets. I use Centurial Pro, an ultra-pure, non-denatured and tasty whey protein and amino acid complex, and have seen excellent results. Each serving of Centurial Pro Complex delivers 25 grams of protein, of which 10.5 grams are BCAA. Improved energy is usually the first benefit, followed closely by an increase in lean muscle mass, a better mood overall, improvements in brain and immune system functions, lower cholesterol levels, plus a higher sensitivity to insulin and improved glucose tolerance… to name just a few. Better energy levels and improved brain function always make exercise easier and more enjoyable, leading to an even greater feeling of well-being.
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